temperature (C); LR: Lethal rate; FTK: Sterilisation time calculated
with the 1st order kinetics and Arrhenius concept. FTD : Sterilisation
time calculated with the D- and Z- value concept.
simulation calculates the required sterilisation time (min) to reach a
given sterility criterion at different temperature. The calculations
are based on the two common concepts: 1st order death rate (k) and its
teperature dependance decribed by the activation energy, and the
concept of decimal reduction time (D) and its temeprature dependance
described by the Z-value. Tempertures in the range of 140 C are used in
continuous sterilisation, while temperature of 121 C is used in
The same theory and models can be used also for pasteurisation (T 60-90 C).
For more information about the theory of sterilisation, see
Fermentation Process Engineering, 2nd ed. (will be available on
information about model equations and parameters: Open
the SIMSPEC-file HTSTsterilisation.fig,
available in the SimuPlot toolbox.